Biomolecular Thermodynamics

“Presents both the principles and equations related to statistical thermodynamics in an original manner that is visually, intuitively, and rigorously. This approach will greatly benefit students at all levels.”
–Vijay S. Pande, Henry Dreyfus Professor of Chemistry, Stanford University

” a masterful feat …. Barrick’s rigor and scholarship come through in every chapter.”
–Rohit V. Pappu, Edwin H. Murty Professor of Engineering, Washington University in St. Louis

This book provides a comprehensive, contemporary introduction to developing a quantitative understanding of how organic macromolecules behave using classical and statistical thermodynamics. The author emphasizes practical skills necessary to apply the underlying equations in real-life examples. The text develops mechanistic models, demonstrating how they relate to thermodynamic observables, presenting simulations of thermodynamic behavior, and analyzing experimental data. The reader is presented with numerous exercises and problems to facilitate hands-on learning through mathematical simulation.