NR566 Advanced Pharmacology Care of the Family Midterm Review LATEST 2021 – 2022 Chamberlain College

Evaluation For NR566 Progressive Pharmacology Care of the Family Midterm Review Latest 2021 – 2022 Chamberlain College

NR 566 / NR566 Progressive Pharmacology Care of the Family Midterm Review| Latest 2021 /2022 | Chamberlain College 1. Learn how to evaluate therapeutic impact of HIV treatment – RNA LEVELS o initial o 2-4 weeks, not after 8 weeks o every 4-8 weeks until suppressed o post-suppressed every 3-4 months – Prolonged virologic suppression for two years o every 6 months – any alteration in status = chemotherapy/steroids o every 3 months 2. Protease Inhibitor (PIs) Lopinavir – high-risk patients – ORAL solution: Inappropriate for full-term infants (until 14 days post birth) and premature (until 14 days post due date) o cardiac disease o History delay QT 3. Protease Inhibitor (PIs) Lopinavir – Lifespan matters – Children: Stable beyond 14 days old – Pregnancy: endorsed with heightened risks 4. Protease Inhibitor (PIs) Lopinavir/ritonavir – negative impacts – – QT prolongation 5. Protease Inhibitor (PIs) Saquinavir – Lifespan concerns – Children o Not verified as stable/efficient in kids younger than 16 – Pregnancy o Safest PI for pregnancy – HIV treatment is advised during pregnancy 6. Protease Inhibitor (PIs) Saquinavir – negative responses – – QT prolongation 7. Nucleoside/nucleotide Reverse Transcriptase Inhibitor (NRTIs). Didanosine (ddI) – high-risk patient – Increase risk of pancreatitis with alcohol use, pancreatitis, and intravenous pentamidine 8. Nucleoside/nucleotide Reverse Transcriptase Inhibitor (NRTIs). Didanosine (ddI) – Lifespan matters – Children o approved at 6 years + weighing 20kg – Pregnancy o Lesser risk 9. Nucleoside/nucleotide Reverse Transcriptase Inhibitor (NRTIs). Zidovudine – Lifespan consideration – Children o neonates – Pregnancy o heightened risk 10. Nucleoside/nucleotide Reverse Transcriptase Inhibitor (NRTIs): Zidovudine – high-risk patients – History of o granulocytosis o low H&H o low vit B12 o low folic acid o current use of medications that induce myelosuppression 11. Learn how to assess therapeutic effect of HIV treatment – CD4 counts o with suppressed RNA levels = increased CD4 levels – Check levels o initial o at 3 month interval o during 1st 2 years every 3-6 months during treatment o long-term suppression – CD4 <300 = every 3-6 months